Furthermore, the size of the reaction vessel is not important. The sample stream can be taken from 5 ml vessels or 10 m³ fermenters. Only 10 microliters per minute are transferred from the continuously flowing sample stream via the membrane into the gas phase. The loss of liquid is therefore very low.
Upscaling of biotechnological processes
The Vario one. offers the best prerequisites to accompany an upscaling of biotechnological processes from laboratory to production scale. In addition, the measured values can be passed on to a process control system, so that measured values from different sensors (e.g. NIR) can be combined for data evaluation. By using porous membranes, dissolved gases and larger molecules, such as alcohols, are simultaneously detected and quantified. Additional sensors such as oxygen and carbon dioxide (pO2, pCO2) sensors are not needed and the contamination risk for the fermentation process can be reduced. Furthermore, the data for the different substance concentrations are available in the same data quality and in real time, which facilitates data evaluation and better process control